Jan 8, 2018 22:08
6 yrs ago
3 viewers *
English term
Russian Federation
10+ years of experience in Pharma
Native in: Russian (Variant: Standard-Russia)
Works in: English to Russian, Russian to English
CYP enzyme activity loss
English to Russian
Medical
Medical: Pharmaceuticals
To evaluate the potential of ХХХХ as a time-dependent CYP inhibitor, the simple one-concentration dilution method was used.
CYP enzyme activity loss of 1A2, 2B6, 2C8, 2C9, 2C19, 2D6 and 3A after pre-incubation with ХХХХ at 10 µM was -15.9%, -0.814%, 7.01%, 13.9%, -4.49%, -19.8% and 5.81%, respectively.
These data suggest that ХХХХ is unlikely to be a time-dependent CYP inhibitor of these 7 major human CYPs.
CYP enzyme activity loss of 1A2, 2B6, 2C8, 2C9, 2C19, 2D6 and 3A after pre-incubation with ХХХХ at 10 µM was -15.9%, -0.814%, 7.01%, 13.9%, -4.49%, -19.8% and 5.81%, respectively.
These data suggest that ХХХХ is unlikely to be a time-dependent CYP inhibitor of these 7 major human CYPs.
Proposed translations
(Russian)
| 4 | Снижение активности изоферментов цитохрома P450 |
Anton Konashenok
|
Proposed translations
24 mins
Anton Konashenok
Czech Republic
Czech Republic
Native in English
&
Russian
Specializes in field
Czech Republic
Competing on quality, not on price
Native in: Russian 
, English
Works in: French to English, Czech to English, Danish to English, and 10 more.
Related KudoZ points
:
143
Selected
Снижение активности изоферментов цитохрома P450
или "ферментов группы цитохрома P450", или "ферментов группы CYP". 1A2, 2B6, 2C8, 2C9, 2C19, 2D6 и 3A - это различные изоферменты этой группы, их полное обозначение - CYP1A2, CYP2B6 и т.д., 3A - это не один изофермент, а подгруппа (3А4, 3А5 и др.).
Вся фраза может выглядеть, например, так: Снижение активности изоферментов цитохрома P450 после инкубации с ХХХХ в концентрации 10 мкмоль/л составило -15,9% для CYP1A2, -0,814% для CYP2B6, 7,01% для CYP2C8, ...
Вся фраза может выглядеть, например, так: Снижение активности изоферментов цитохрома P450 после инкубации с ХХХХ в концентрации 10 мкмоль/л составило -15,9% для CYP1A2, -0,814% для CYP2B6, 7,01% для CYP2C8, ...
4 KudoZ points awarded for this answer.
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